Concentration and Purification of Viruses by Using Ultrafiltration, incl. Coronavirus - a Short Review
This short review highlights concentration and purification steps of various viruses in the context of different research applications. The discussed methods find application in medical research, marine biology as well as in research concerning drinking water and food quality. You will find a guidance for the selection of an ideal performing ultrafiltration device with the optimum molecular weight cut-off (MWCO) for typical concentration applications.
With the emergence of the COVID-19 global pandemic, the large Coronavirus family of viruses has come to the forefront of immunology, epidemiology and vaccinology studies. Investigations into general Coronavirus virology, Coronavirus spike proteins, capture of Coronavirus virons and free RNA from water streams, are three core examples of focus points for study in the scientific community, as such we provide some examples of concentration and purification steps in these Coronavirus research workflows.