Improved Car-T Cell Expansion in Ambr® 250 High-Throughput Bioreactor

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Improved Car-T Cell Expansion in Ambr^® 250 High-Throughput Bioreactor

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Improved Car-T Cell Expansion in Ambr^® 250 High-Throughput Bioreactor

Expanding patient CAR-T cells ex vivo is the longest phase of manufacturing. To meet rising demand and reduce costs, manufacturers need scalable expansion processes that maximize yield and reduce vein-to-vein time.

In this study, we optimize perfusion parameters in a single-use, automated stirred-tank bioreactor to reduce process time and increase yield for allogeneic modalities.

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Improved Car-T Cell Expansion in Ambr® 250 High-Throughput Bioreactor

Improved Car-T Cell Expansion in Ambr® 250 High-Throughput Bioreactor

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Improved Car-T Cell Expansion in Ambr^® 250 High-Throughput Bioreactor

Improved Car-T Cell Expansion in Ambr^® 250 High-Throughput Bioreactor