Combo Dye® and ViroTag® Reagents

Virus Counter® Reagents

Rapid, Direct, Biologically Relevant Virus Quantitation

The Virus Counter® platform, Combo Dye® and ViroTag® reagents, were specially developed to quantify viruses rapidly and with high specificity utilizing the Virus Counter® instrument. The reagents offer a biologically-relevant readout with versatility to address unique quantification needs.  Virus samples stained with Combo Dye® or ViroTag® reagents are quantified after a 30 minute incubation. ComboDye® reagent is based on a dual stain approach that uses fluorogenic dyes to detect virus particles. The reagent can be used for quantification of all enveloped viruses. The ViroTag® reagent product line is based on an antibody-driven recognition of virus particles. Antibodies selected in the ViroTag® reagents are labeled with fluorophores and are highly specific for indicated viruses.

Choose the Optimal Reagent for Every Virus Sample

ViroTag® Reagent

The ViroTag® detection system provides mission-critical data in real-time. This novel technology enables direct, biologically specific quantification of viruses. by utilizing a fluorescently-labeled, high-affinity antibody which binds to a unique epitope expressed by your virus of interest.

Use the ViroTag® reagents to label your virus samples and analyze on the Virus Counter® instrument. 
Enables real-time tracking of virus titer in your process:

  • Optimize growth conditions
  • Maximize yields
  • Identify problems sooner

ViroTag® Reagent Kits

Code     

AAV2-3

for Adeno-Associated Virus Serotypes 2, 3

BCVB

for Baculovirus

VSVG

for pseudo typed viruses such as Lentivirus or BacMam

INVA

for Influenza A seasonal flu virus

INVB

for Influenza B seasonal flu virus


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The Virotag® DY detection system is a ready-to-use, simple, and universal approach for virus quantification. This reagent is compatible with all enveloped viruses, with single or double-stranded DNA or RNA genome. This universal reagent is based on a dual strain approach that identifies intact virus particles by simultaneous detection of protein and nucleic acid signal. The use of fluorogenic dyes eliminates the need to wash.

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Virus families successfully quantified with Combo Dye®

Arenaviridae
Pichinde virus

Baculoviridae
Baculovirus

Coronaviridae
Coronavirus
Infecious bronchitis virus

Flaviviridae
Dengue virus
Zika virus

Filoviridae
Ebola virus
Marburg virus

Herpesviridae
Herpes Simplex Virus I
Cytomegalovirus

Orthomyxoviridae
Influenza virus

Paramyxoviridae
Measles virus
Newcastle disease virus

Poxviridae
Pox virus
Vaccinia virus

Retroviridae
Lentivirus
y-Retrovirus

Rhabdoviridae
Rabies virus
Vesicular Stomatitis virus

Togaviridae
Chikungunya

Downloads

Poster: Rapid Total Particle Quantification for Viral Families With High Potential for Pathogenic Emergence

PDF | 1.5 MB

Poster: Rapid, Real Time Quantification of Adeno-Associated Virus Particles Using Antibody-Based Detection on the Virus Counter® 3100

PDF | 1.3 MB

Flyer: Virotag® INVA & Virotag® INVB Reagents 

PDF | 285.8 KB

Application Note: Rapid, Real Time Quantification of Lentivirus Particles Using Antibody-Based Detection on the Virus Counter® 3100 Platform

PDF | 103.5 KB

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