On-Demand Webinar: Optimizing Organoid Culture for Development and Disease Modeling
Duration: 1 hour
Overview
Three-dimensional (3D) cell culture models, such as organoids, allow scientists to mimic intricate biological functions and the properties of tissues within a manageable laboratory environment. Nonetheless, developing high-quality organoid models poses distinct challenges for researchers.
In this on-demand Technique Talk from The Scientist and sponsored by Sartorius, Aitor Aguirre, Associate Professor at Michigan State University, shares insights on his team's process of creating cardiac organoids from induced pluripotent stem cells (iPSCs) and how they use these 3D cell models to explore the intricacies of human heart development and investigate various heart diseases.
Key Takeaways
- Cultivating and plating induced pluripotent stem cells (iPSCs) in three-dimensional structures for the development of heart organoids
- Understanding the processes involved in cardiac mesoderm and proepicardial induction
- Maintaining and maturing organoids over extended culture periods
- Utilizing heart organoids for disease modeling research
Webinar Speaker
Aitor Aguirre, PhD
Associate Professor
Institute for Quantitative Health Science and Engineering
Department of Biomedical Engineering
Michigan State University