Sartorius MSC Exploration and Characterization Solution

A high-throughput, automated solution that enables media and microcarrier screening and CPP identification through experimental design, with insight-delivering analytics to establish and track CQAs for effective transition from planar to suspension–based MSC culture.

  • Process control: Control pH, DO, temperature and stirring speed as you explore the expansion process of MSCs in 10 - 15 mL cultures with consistent, serum-free, xeno-free MSC medium
  • Automation: Reduce setup, execution, and variability of DoE studies with automated liquid handling during MSC expansion in a bioreactor platform coupled with walkaway automation flow cytometry and live cell analysis
  • At-scale throughput: Set up comprehensive DoE approaches with use of minimal MSCs and reagents in a 24 - 48 parallel mini bioreactor system and perform functional cell characterization assays in 96- and 384-well plates
  • Extensive characterization: Monitor MSC morphology and growth using live-cell analysis and assess the paracrine effects using an advanced flow cytometry system
  • Process insight: Develop greater process understanding using design of experiments software with phenotypic and functional characterization insights
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Ambr® 15 Cell Culture

High-throughput, automated microbioreactor system for 24 - 48 parallel cultivations at 10 - 15 mL scale

MODDE®

Design of experiment software to enable a seamless transition from planar to suspension culture while identifying critical process parameters

MSC NutriStem® XF Basal Media

Defined, serum-free, xeno-free MSC expansion medium to maintain normal morphology, stable karyotype, and trilineage differentiation potential

SoloHill® Microcarriers

Sterile, ready-to-use microcarriers in a variety of formats that support rapid and efficient attachment and growth of MSCs in suspension culture

NutriFreez® D10 Cryopreservation Medium

Fully defined, serum-free cryopreservation medium for a consistent, high-performance protective environment for MSCs during freezing, storage, and thawing

MSCgo™ Differentiation Media

Serum-free, xeno-free MSC trilineage differentiation potential testing (osteogenic, adipogenic, and chondrogenic)

Microsart® ATMP

3-hr PCR-based kit for the detection of mycoplasma, bacteria, and fungi for in-process testing of MSC therapeutics

Centrisart® G-16C

High-capacity refrigerated bench top centrifuge with microbioreactor adapters to enable media exchange and endpoint harvesting in the Ambr® 15 platform

Ambr® 15 Cell Culture

High-throughput, automated microbioreactor system for 24 - 48 parallel cultivations at 10 - 15 mL scale

MODDE®

Design of experiment software to enable a seamless transition from planar to suspension culture while identifying critical process parameters

iQue® 3

Advanced high-throughput flow cytometry platform for MSC phenotypic analysis and immunomodulation and cytokine profiling assessment

Incucyte® SX5

Automated, real-time, live-cell analysis platform for quantitative insights into MSC health, morphology, proliferation, and function

iQue® 3

Advanced high-throughput flow cytometry platform for MSC phenotypic analysis and immunomodulation and cytokine profiling assessment

Incucyte® SX5

Automated, real-time, live-cell analysis platform for quantitative insights into MSC health, morphology, proliferation, and function

Ambr® 15 Cell Culture

High-throughput, automated microbioreactor system for 24 - 48 parallel cultivations at 10 - 15 mL scale

MODDE®

Design of experiment software to enable a seamless transition from planar to suspension culture while identifying critical process parameters

Incucyte® SX5

Automated, real-time, live-cell analysis platform for quantitative insights into MSC health, morphology, proliferation, and function

iQue® 3

Advanced high-throughput flow cytometry platform for MSC phenotypic analysis and immunomodulation and cytokine profiling assessment

SIMCA®

Powerful multivariate data analysis tool with interactive visualizations, an intuitive interface, and automatable workflows for comprehensive process understanding

Sartorius MSC Exploration and Characterization Solution Data Sheet Collection

PDF | 17.3 MB

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