Sartorius MSC Exploration and Characterization Solution
A high-throughput, automated solution that enables media and microcarrier screening and CPP identification through experimental design, with insight-delivering analytics to establish and track CQAs for effective transition from planar to suspension–based MSC culture.
- Process control: Control pH, DO, temperature and stirring speed as you explore the expansion process of MSCs in 10 - 15 mL cultures with consistent, serum-free, xeno-free MSC medium
- Automation: Reduce setup, execution, and variability of DoE studies with automated liquid handling during MSC expansion in a bioreactor platform coupled with walkaway automation flow cytometry and live cell analysis
- At-scale throughput: Set up comprehensive DoE approaches with use of minimal MSCs and reagents in a 24 - 48 parallel mini bioreactor system and perform functional cell characterization assays in 96- and 384-well plates
- Extensive characterization: Monitor MSC morphology and growth using live-cell analysis and assess the paracrine effects using an advanced flow cytometry system
- Process insight: Develop greater process understanding using design of experiments software with phenotypic and functional characterization insights
Ambr® 15 Cell Culture
High-throughput, automated microbioreactor system for 24 - 48 parallel cultivations at 10 - 15 mL scale
MODDE®
Design of experiment software to enable a seamless transition from planar to suspension culture while identifying critical process parameters
MSC NutriStem® XF Basal Media
Defined, serum-free, xeno-free MSC expansion medium to maintain normal morphology, stable karyotype, and trilineage differentiation potential
SoloHill® Microcarriers
Sterile, ready-to-use microcarriers in a variety of formats that support rapid and efficient attachment and growth of MSCs in suspension culture
NutriFreez® D10 Cryopreservation Medium
Fully defined, serum-free cryopreservation medium for a consistent, high-performance protective environment for MSCs during freezing, storage, and thawing
MSCgo™ Differentiation Media
Serum-free, xeno-free MSC trilineage differentiation potential testing (osteogenic, adipogenic, and chondrogenic)
Microsart® ATMP
3-hr PCR-based kit for the detection of mycoplasma, bacteria, and fungi for in-process testing of MSC therapeutics
Centrisart® G-16C
High-capacity refrigerated bench top centrifuge with microbioreactor adapters to enable media exchange and endpoint harvesting in the Ambr® 15 platform
Ambr® 15 Cell Culture
High-throughput, automated microbioreactor system for 24 - 48 parallel cultivations at 10 - 15 mL scale
MODDE®
Design of experiment software to enable a seamless transition from planar to suspension culture while identifying critical process parameters
iQue® 3
Advanced high-throughput flow cytometry platform for MSC phenotypic analysis and immunomodulation and cytokine profiling assessment
Incucyte® SX5
Automated, real-time, live-cell analysis platform for quantitative insights into MSC health, morphology, proliferation, and function
iQue® 3
Advanced high-throughput flow cytometry platform for MSC phenotypic analysis and immunomodulation and cytokine profiling assessment
Incucyte® SX5
Automated, real-time, live-cell analysis platform for quantitative insights into MSC health, morphology, proliferation, and function
Ambr® 15 Cell Culture
High-throughput, automated microbioreactor system for 24 - 48 parallel cultivations at 10 - 15 mL scale
MODDE®
Design of experiment software to enable a seamless transition from planar to suspension culture while identifying critical process parameters
Incucyte® SX5
Automated, real-time, live-cell analysis platform for quantitative insights into MSC health, morphology, proliferation, and function
iQue® 3
Advanced high-throughput flow cytometry platform for MSC phenotypic analysis and immunomodulation and cytokine profiling assessment
SIMCA®
Powerful multivariate data analysis tool with interactive visualizations, an intuitive interface, and automatable workflows for comprehensive process understanding
