Cell Culture Adaptation & Cell Line Adaptation
Many processes use traditional anchor-dependent and serum-supplemented mammalian cell culture, but the serum and animal-derived components come with a series of disadvantages. In contrast, suspension cultures in animal-component-free (ACF) cell culture media have several benefits:
- Reduced lot-to-lot variability
- Easier scale-up
- Avoids risk of blood-borne pathogens
- Cost savings in production
Transitioning from Adherent to Suspension
Suspension cultures in ACF cell culture media can support industrial processing and scale-up more efficiently than adherent cells, making them a great choice for recombinant protein and viral vector production. Our experts can help you ease the transition from adherent to suspension serum-free culture.
Cell Culture Adaptation
When adapting your cell culture, it’s critical to consider the different environments that it will be exposed to. Based on your existing process conditions and expected quality attributes improvement, we create a strategy that optimizes your cells throughout your process.
Cell Line Adaptation
Make it easy to adapt your adherent culture to suspension growth in the serum-free, chemically defined cell culture media of your choice. With more than 20 years of experience in cell culture and state-of-the-art culture media, our experts help you streamline your cell line adaptation in less time.
