Sistemas de expresión de proteínas

Exprese su proteína a través del desarrollo de procesos de ingeniería

La expresión proteica es un requisito fundamental en el ciclo de desarrollo de fármacos. Nuestros sistemas de expresión de proteínas líderes comienzan en el desarrollo de la línea celular, en la cual hemos trabajado con más de 75 líneas celulares, a través de la fabricación y caracterización de los bancos celulares, ambos completamente conformes con cGMP.

Achieve high performing titers

Proven by >75 cell lines, with 95% expressing 3 - 8 g/L

Discover More

Manufacture your cell banks in our closed-system facility

Our new closed-system, single-use and fully cGMP compliant facility ensures your cell banks are manufactured to the highest of standards

Find out More

Over 150 characterized cell banks

With over 10 years' experience in cell bank characterization, working with over 50 different clients, we are your experts.

Talk to Our Experts

Benefit from our total solution

Cell Line & Upstream Process Development

We are leading providers of cell line and upstream process development services for large-scale protein production of biopharmaceuticals in mammalian (CHO) cells, specifically for the industrial production environment.

Based on our in-depth expertise, know-how, and intellectual property, we have devised a unique CHO Expression Platform, which is the most competitive system available on the market. The platform delivers a high yielding, stable cell line, and robust, simple, fed-batch process via 4 key components which takes your product from DNA to RCB in just 4 months:

  •     Expression Vector
  •     Host Cell Line
  •     CHO Media System
  •     Upstream Process Design

Our extensive experience and expertise allow us to work with difficult to express proteins, and the consistency of our CHO Expression Platform is evident in our successful track record by consistently producing titers of 3 g/L or more, plus market approval.

Cell Bank Manufacturing & Characterization

We pride ourselves in providing an industry leading closed-system, single-use and fully cGMP compliant cell banking manufacturing process with comprehensive PAT options available. Our facility offers:

  •     Automatic vial filling system
  •     500 vial cell banks at 1-3x10⁷ cells per vials
  •     Controlled rate cryopreservation
  •     Fully integrated cell bank testing services

We also provide comprehensive cell bank characterization which is vital for safety and control of the product to ensure it is free from adventitious agents.

All our cell bank characterization services are conducted to cGMP standards and according to ICH Q6B guidelines, providing experienced and expert advice on the most efficient testing package to suit your drug development requirements.

Explore Sartorius

Cell Line Development

Learn More

Cell Bank Manufacturing

Learn More

Cell Line Characterization

Learn More