Influence of a Built-In Crossflow Ultrafiltration Module on the TOC Level in Ultrapure Water
Authors: Dr. Herbert Bendlin
Overview
The success and reliability of analytical technologies such as HPLC, GC-MS, and ICP-MS are highly dependent on the use of ultrapure water. As these methods have become more sensitive, they have also become more susceptible to interference from trace levels of contaminants in the buffers and solutions used. This has led to increased quality requirements for the various system components and consumables.
The following water purification technologies have been proven in recent years to provide the high-quality ultrapure water required for these applications.
For applications requiring particularly low levels of total organic carbon (TOC) in the product water, initial water purification is typically performed using activated carbon and particulate filters, followed by reverse osmosis technology (with an EDI stack as an option). These processes typically remove 95-98% of the contaminants found in water (e.g., salts, particles, and organic compounds). The final purification steps are performed by an Ultrapure Water System, which produces product water that meets or exceeds the ASTM Type I water standard.
This technical note discusses the influence of a built-in crossflow ultrafiltration module on the TOC level in ultrapure water.
- Document type: Technical Note
- Page count: 4
- Read time: 8 minutes
Key Takeaways
- Ultrapure water is crucial for reliable analyses in analytical technologies such as HPLC, GC-MS, and ICP-MS.
- Water purification technologies, including activated carbon, particulate filters, and reverse osmosis, effectively provide high-quality ultrapure water by removing up to 98% of contaminants.
- Built-in Ultrafiltration (UF) using crossflow filter systems effectively removes remaining enzymes and nucleic acids from water, reducing TOC values.
- The built-in Sartorius UF membrane in the Arium® Pro Ultrapure Water Systems uses crossflow filtration technology, reducing membrane fouling and blockage, and decreasing environmental impact and cost.
This Resource is Designed for:
- Lab Researchers
- Lab Technicians
- Analytical Lab
- Quality Control
- Beverage Producers
Applications Supported:
- Life Science Research
- Analytical Quality Control
- Total Organic Carbon (TOC)
- Built-in Ultrafiltration (UF)
- Molecular Weight Cut Off (MWCO)
- General Water Use
- HPLC Analysis
- Water Purification
- Water Impurities
- Ultrapure Water
- ASTM Type 1 Water
