Sartoflow® 150 Small-Scale Single-Use Tangential Flow Filtration System
Optimized Small-Scale Single-Use TFF Processing
The Sartoflow® 150 single-use tangential flow filtration (SUTFF) system is easy to use and offers all of the critical sensors for running ultrafiltration (UF) and diafiltration (DF) processes for 2 – 20 L batch volumes. The system layout features a minimum recirculation loop to ensure final target volumes are achieved while providing excellent product recovery.
Device Country Availability | Sartoflow® 150 is only available in North America.
Designed for efficiency in SUTFF applications with batches from 2 L up to 20 L using 0.1 m2 – 0.4 m2 TFF cassettes.
A range of single-use sensors provide the flexibility to measure pressure, flow, conductivity, temperature and UV
Low-shear 4-piston membrane pump is suitable for low-shear applications, enabling a flow range of 5 to 150 L per hour
Single-Use TFF for Smaller Batch Volumes
The Sartoflow® 150 is a semi-automated single-use tangential flow filtration system (SUTFF) designed for pilot or small-scale process ultrafiltration and diafiltration (UF/DF) applications of 2–20 L batch volumes.
- Easy to use
- Single-use sensors
- Low recirculation volume
- Excellent product recovery
- 0.1 – 0.4 m2 cassette area
- Automated transmembrane pressure (TMP) control
System Functionality
The Sartoflow® 150 system is designed to generate scalable data in small-scale process development activities and is compliant with good manufacturing practice (GMP) regulations. The Sartoflow® single-use components and design approach are consistent across our SUTFF systems so that projects can be scaled up from the Sartoflow® 150 system to the larger Sartoflow® SUTFF systems.
Control System
The Sartoflow® 150 offers automated transmembrane pressure (TMP) control and retentate biocontainer weight control. Operators can set the diafiltration pump to automatically control the pump speed to maintain a constant mass in the retentate biocontainer according to the defined input weight.
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Learn More About Sartoflow® 150
General Specification | |
Weight | 115 kg |
Dimensions | 1,079 × 764 × 1,228 mm (nominal) |
cGMP | CFR21 Part 11 available |
System Specification | |
Membrane Area | 0.1 m2 – 0.4 m2 |
Vessel Volume | 5 L, 10 L or 20 L |
Flow Rate / Pump Capacity - Recirculation | Flow range 5-150 L/h |
Flow Rate / Pump Capacity - Media Addition Pumps | Up to 54 L/h |
Minimum Recirculation Volume | 130 mL |
Process Mode (Multi-Use / Single-Use) | Single-Use |
Max Pressure | 4 barg | 58 psig |
Wettware Specification | |
Tube ID | 3/8" (9.6 mm) feed/retentate |
Sensor Options | Pressure, flow, conductivity, temperature & UV |
