Application Note: MSC Differentiation with Non-Invasive Monitoring and HTS Cytometry
Authors: Natasha Lewis, Jasmine Trigg, Daryl Cole, Nicola Bevan
Last updated: September 2024
Overview
Mesenchymal stem cells (MSCs) are adult stem cells known for their ability to differentiate into multiple cell types and their strong immunomodulatory properties, making them highly valuable in regenerative medicine, tissue engineering, and cell therapy. To ensure their therapeutic effectiveness, it's crucial to rigorously confirm their ability to differentiate into specific cell types, such as osteoblasts and adipocytes.
Traditional endpoint assays for assessing MSC differentiation often fall short in providing dynamic insights, underscoring the need for advanced technologies that offer real-time, high-throughput, and multiparametric analysis.
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- Document type: Application Note
- Page count: 10
- Read time: 10 minutes
Key Takeaways
Learn more about the importance of assessing MSC differentiation in real-time:
- Technologies that allow for continuous live-cell imaging and rapid, multiplexed analysis, providing a comprehensive view of the differentiation process
- Faster confirmation of differentiation potential and preservation of cellular material for further analysis, enhancing the efficiency and reliability of MSC research
- Enable valuable insights into the dynamics of the differentiation process
