eBook: Harnessing the Power of T Cells
Authors: Biocompare | Last updated: February 2022
Overview
Chimeric antigen receptor-T cell (CAR-T) therapies have tremendous potential for cancer treatment. However, developing these therapies can be complicated as CAR-T cells must be continually monitored for quality and functionality during production. A myriad of technologies is used to ensure appropriate cell types are isolated, their phenotype assessed, and their expansion monitored.
- Document type: eBook
- Page count: 56
- Read time: 1.5 hours
This eBook focuses on the use of advanced flow cytometry and live-cell analysis in CAR-T development, discussing:
- Optimization of T cell isolation, engineering, activation and expansion
- Phenotypic and functional characterization of CAR-T cells
- Use of live-cell imaging and analysis to gain immunological insights
- Evolution of immune cell killing assays