Harnessing the Power of T Cells

eBook: Harnessing the Power of T Cells

Authors: Biocompare | Last updated: February 2022

Overview

Chimeric antigen receptor-T cell (CAR-T) therapies have tremendous potential for cancer treatment. However, developing these therapies can be complicated as CAR-T cells must be continually monitored for quality and functionality during production. A myriad of technologies is used to ensure appropriate cell types are isolated, their phenotype assessed, and their expansion monitored.

  • Document type: eBook
  • Page count: 56
  • Read time: 1.5 hours

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Key Takeaways

This eBook focuses on the use of advanced flow cytometry and live-cell analysis in CAR-T development, discussing: 

  • Optimization of T cell isolation, engineering, activation and expansion 
  • Phenotypic and functional characterization of CAR-T cells
  • Use of live-cell imaging and analysis to gain immunological insights
  • Evolution of immune cell killing assays
     

Using Live-Cell Imaging and Flow Cytometry for CAR-T Cell Characterization

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