App Note: Long-Term Live-Cell Assays with ChromaLIVE® Non-Toxic Dye and Live-Cell Analysis

Last updated: February 2025 

Overview

This application note reveals the non-toxic nature of ChromaLIVE™ on cell proliferation and its ability to deliver precise cell counts and kinetic insights together with a streamlined workflow for integrating raw image data - demonstrating the unique kinetic insights that can be captured from combining these two live-cell technologies.

Incucyte® Advanced Live-Cell Imaging
Incucyte® Live-Cell Imaging and Analysis offers an optimal environment, ensuring cells remain stationary in a stable incubator setting during image collection. With up to 5 fluorescent channels, label-free phase contrast, and low phototoxicity near-infrared (NIR) channels, the Incucyte® system provides a comprehensive suite of features. Its flexible, user-friendly multi-user software enhances your research capabilities.

ChromaLIVE™ Multi-Chromatic Fluorescent Dye
Experience high-density biological information with ChromaLIVE™, a non-toxic, multi-chromatic fluorescent dye. Designed to minimize disruption to cellular physiology, ChromaLIVE™ enables the tracking of diverse cellular phenotypes in vitro over extended periods. Gain unique kinetic insights and accurate cell counts with this revolutionary technology.

  • Document type: Application Note
  • Page count: 5
  • Read time: 6 minutes

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Key Takeaways

  • Versatility & Compatibility: ChromaLIVE™ seamlessly integrates with the Incucyte® system, offering unique insights into cell responses to treatments.
  • Long-term Analysis: Perfect for long-term kinetic studies, allowing for detailed quantification of complex biological changes.
  • Innovative Insights: Provides unique fluorescence intensity signatures, enhancing our understanding of compound mechanisms.

Application Note Preview

Figure 1.  Cover image of Long-Term Live-Cell Assays with ChromaLIVE® Non-Toxic Dye and Live-Cell Analysis application note
 

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