Vivaflow® SU Extractables Technical Note

Last updated: May 2025

Overview

Purification consumables may contain substances that are hazardous to health, or leach extractables into samples that will compromise downstream experiments.

This technical note presents the extractables profile for Vivaflow® SU and the materials of construction from which these substances originate. Data are presented for cassettes with PES or Hydrosart® RC membranes. It also confirms that Vivaflow® SU is DEHP-free and concludes that there are no extractable substances which would negatively impact on cell growth.

The results and conclusions are intended to support decision making when designing and implementing lab-scale TFF processes, helping to ensure sample integrity and reliable results.

Resource Details:

  • Document Type: Technical Note
  • Page Count: 8
  • Read Time: 10 Minutes

 

Key Takeaways:

  1. View the extractables profile for Vivaflow® SU and learn the origin of each extractable substance
  2. Understand that extractable substances differ based on your chosen membrane chemistry
  3. Recognize that there are no REACH substances and that the extractables do not affect cell growth
  4. Decide whether to use a flushing step before processing your sample with Vivaflow® SU

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This Resource is Designed for:

  • Process Development Scientists
  • Purification Scientists
  • Research Scientists

Applications Supported:

  • Diafiltration
  • Tangential Flow Filtration
  • Ultrafiltration

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