On-Demand Webinar: Laboratory Solutions for AAV and LV Downstream Processing – How to Purify Viral Vectors in Small Scale
Authors: Andreas Pickl, PhD
Overview
In this webinar, our expert provides insights into the downstream processing of adeno-associated viruses (AAV) and lentiviral vectors (LV), focusing on small-scale purification challenges and solutions. We highlight innovative laboratory solutions designed to tackle common challenges such as filter clogging and large volume processing. By employing advanced techniques like diatomaceous earth (DE) for enhanced filtration efficiency, and utilizing advanced devices such as Vivaspin® and Sartobind® Convec D, researchers can significantly improve recovery rates while minimizing damage to viral vectors.
Key Takeaways
- Understanding challenges in AAV and LV downstream processing
- Solutions for filter clogging and large volume processing
- Methods to improve viral vector recovery and reduce processing time
- Recommendations for purification and formulation steps
Webinar Speaker
Andreas Pickl, PhD
Manager of Lab Separations Applications Sartorius
Andreas Pickl is Manager of Lab Separation Applications at Sartorius. With an extensive background spanning more than five years, he has garnered expertise in product development and the practical implementation of body feed filtration solutions for mammalian cell broths. His commitment revolves around aiding customers in conquering the hurdles linked with the filtration of challenging cell broths and the further DSP steps for different modalities such as monoclonal antibodies, AAV and LV. Andreas holds a master’s degree and a PhD in biochemistry.
