Benefits of Using Octet® BLI Systems in IVD Product Development

Authors: Shuo Liang, Hasret Altan-Martin, Christin Ronsör, David Apiyo | Last updated: July 2023

Overview

A lateral flow assay (LFA) is one of the most common immunoassay formats for in vitro diagnostics (IVD), in which antibodies play a critical role. The quality characteristics of antibodies and their interaction with antigens affect the test performance of LFAs. A deep understanding of antibody-antigen interactions and antibody quality is essential for the development and optimization of LFAs.

The Octet® system is a powerful and easy-to-use high-throughput solution for analyzing antibody-antigen interactions. Download our white paper to learn how the Sartorius Octet® BLI system enables real-time, label-free, high-throughput monitoring of antibody-antigen interactions and provides critical insights useful in designing a high-performing LFA test.


  • Document type: White Paper
  • Page count: 6
  • Read time: 11 minutes


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Key Takeaways

  • Quality control of antibodies using the Octet® System
  • Determination of binding specificity using the Octet® System
  • Binding kinetics and affinity and their effect on LFA performance
  • Optimization of an LFA using the Octet® System

This Resource is Designed for:

  • Analytical Lab Assistants
  • Engineers
  • Lab Researchers
  • Assay Developers
  • Quality Control Scientists
  • Scientists

Applications Supported:

  • Lateral Flow Assays (LFA)
  • In Vitro Diagnostics (IVD)
  • Binding Kinetics
  • Antibodies' Quality
  • Antibody-Antigen Interaction

The Role of Octet® Systems in LFA Development

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