Process development is driven by designing processes for a wide range of expression systems in order to establish the appropriate process parameters that will result in successful scale up and robust cGMP manufacturing.
In this webinar, Olga Morejón Zayas, Head of Process Development at 3P Biopharmaceuticals, will present her work with Ambr® 250 on three experimental packages used to define the optimal process parameter to support high cell density culture of CHO DG44 cells to improve productivity and scalability.
What You Will Learn:
- Gain overview of recent developments on the Ambr250 ht for upstream process development
- Learn how to use the Ambr250 ht and integrated at-line metabolite analyzers for rapid media and feed screening, followed by feeding strategy and process parameter optimization, all in a small-scale, automated high-throughput approach
- Hear about how 3P Biopharmaceuticals was able to increase productivity, reaching >15g/L of product, by intensifying an optimized CHO process