Experience the Future of Biotherapeutic Drug Development together at this year’s PEGS Boston
May 13 – 17, 2024 | Boston, MA
OMNI Boston Hotel at the Seaport
Join Sartorius at the world’s largest protein engineering and biotherapeutics summit - the leading biologics event with comprehensive programming covering all aspects of biologic drug development with in-depth presentations on protein and antibody engineering, immunotherapy, oncology, expression, analytics, immunogenicity, and more.
Make sure to visit us at booth 211 to become part of the PEGS community together.
Sartorius at this year's event
Presentation Details
Track: Engineering Antibodies
Date/Time: Wednesday, May 15 @ 4pm
Title: Combining Binding and Functional Analyses for Comparison of Anti-TNFα Monoclonal Antibody Biosimilars
To exemplify the use of a combined cell analysis and ligand binding for the characterization of biosimilars, a range of binding and functional characteristics was assessed on Adalimumab antibodies. An Adalimumab clone was subjected to an elution buffer optimization process, with the resulting elution fractions of the antibody assessed using single concentration analyte kinetic screen an against an antigen and a set of Fcγ receptors; CD16a V176 and CD64.
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The 2024 conference will feature 8 tracks of educational content:
Speaker Information
David O. Apiyo, PhD
Manager of Application Development
David is currently Manager of BioAnalytics Applications Development at Sartorius and has more than 15 years of experience in label-free biomolecular interaction analysis. Before joining Sartorius, he was a Senior Scientist at Beckman Coulter. He obtained his PhD in Chemistry at Tulane University and has held multiple Postdoctoral research positions.
Featured Products
Unmatched flexibility and versatility in protein analysis with an 8-channel fluidic-free design compatible with longer experimental run times and seamless integration into GxP-compliant labs during biologics development.
Generate high-quality kinetics and affinity data in a fraction of the time compared to standard multi-cycle kinetics using innovative gradient injections.
CellCelector Flex Single Cell & Colony Retrieval System
Fully automated image-based analysis, screening, sorting and retrieval of single cells, clones, clusters and adherent cell colonies used in a multitude of research areas including antibody discovery.
iQue® 3 High-Throughput Screening Cytometry Platform
Profile cell productivity running multiplexed assays to enable simultaneous reporting of IgG quantity, cell number and cell viability in the same sample during cell line production.
Testimonial
“For me, the PEGS conferences are an important and continuous source to develop new ideas for research and product development. Every visit is a deep dive into a world full of science, insights, and ideas I can discuss with so many scientists establishing new collaborations and networks. Based on these interactions and ideas, PEGS has been the beginning for a significant number of new R&D projects in my career.” - Dennis Karthaus, Sartorius Xell GmbH
