How Smart Analytics Transform Manufacturing – an interview with UCL
UCL partnered with Sartorius to rethink CAR‑T manufacturing for speed, scale, and consistency. In this video, Pierre Springuel explains how combining ambr® bioreactors with Incucyte® live‑cell analysis and the iQue® high‑throughput cytometer enabled data‑driven process optimization. By continuously monitoring cell growth, phenotype, and functional killing, the team halved the time to generate a CAR‑T dose and more than quadrupled weekly dose output—without compromising potency. The interview explores how integrated bioanalytics and smart experimental design can unlock intensified, scalable CAR‑T processes and help bring advanced cell therapies to more patients.
Key takeaways:
- UCL halved CAR-T manufacturing time while maintaining potency
- ambr®, Incucyte®, and iQue® enabled data driven process optimization
- Continuous CQA monitoring protected phenotype and function
- Weekly CAR-T dose output more than quadrupled
- Explore an approach that supports faster, scalable auto and allogeneic CAR-T
Resource details:
- Document type: Video
- Watch time: 09:49