Overview
Trace analysis in HPLC-DAD and LC-MS depends heavily on the purity of the water used as an eluent. Even minor contaminants can increase background noise, suppress signals, and reduce method sensitivity and reproducibility. This application note evaluates different ultrapure water sources and their impact on analytical performance. It highlights how freshly purified water can significantly improve data quality by minimizing contamination risks associated with storage and handling. Learn how choosing the right water source can enhance reliability, sensitivity, and consistency in trace-level analytical workflows.
What you will learn:
- Why water purity directly impacts HPLC and LC-MS performance
- How contaminants and storage affect trace analysis results
- Benefits of using freshly purified ultrapure water
- How to improve sensitivity, baseline stability, and reproducibility in analytical workflows
Resource details:
- Document type: Application note
- Page count: 9
- Read time: 12 minutes
