Why Ultrapure Water is Essential for Consistent, Reproducible Endotoxin Results

Authors: Rapidmicrobiology | Last updated: May 29, 2023

Overview

Have you ever wondered why endotoxin testing is crucial? Endotoxins are toxic substances found in the outer membrane of Gram-negative bacteria, and they can cause severe reactions in humans, including fever, shock, and even death.

It is essential to ensure that products are free from endotoxins. However, achieving accurate and reliable endotoxin results requires more than endotoxin-free plastic ware and the right testing methods. A key potential source of endotoxin contamination can be the lab water supply.

In this rapidmicrobiology interview with Dr. Kunal Kureja, Application Scientist for Lab Water at Sartorius AG, you’ll explore what type of ultrapure water is suitable for use in endotoxin analysis and how to validate and verify it is endotoxin-free.


  • Document type: Article
  • Read time: 10 minutes


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Key Takeaways

  • What type of ultrapure water is suitable for endotoxin analysis
  • How to validate and verify that your water is endotoxin free
  • Guidelines to help you choose the right grade of ultrapure water
  • Best practices and potential pitfalls in handling ultrapure water
  • Other contaminants that may play a role in quality testing labs
  • The benefits of Arium® systems

This Resource is Designed for:

  • Pharmaceutical Professionals

  • Biotech Professionals

  • Medical Device Manufacturers

  • Environmental Testing Professionals

  • Researchers in the Field of Microbiology

Applications Supported:

  • Analytical Applications
  • General Water Use
  • Water Purification
  • Endotoxin Testing
  • Water Impurities
  • Ultrapure Water

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