SIMCA® 18

SIMCA® is the Sartorius software for multivariate data analysis.

This is new in SIMCA 18:

Adaptive Process Mode – enable combined use of steady-state and dynamic phase data in batch projects
Calibration Transfer – support for adapting models to change in instrument settings
Improved import – including performance for database and formatting and support for resolving issues
Scripting improvements – with the aim to enhance the overall user experience for scripting in SIMCA®
Bundled Python example scripts – easily create and test forecast models for Control Advisor in SIMCA-online, and support for scalable model maintenance
Python 3.10.2 is bundled with SIMCA (optional feature in installation)
Rearrange order of phases – ability to correct model order after import and add additional phase data
Correlation matrix – updated color scheme and editable number format
Orthogonal component visualization – updated default loading plots for OPLS models
Generate variable from qualitative – added support to specify variable output based on categorical variables
Secondary Batch ID in batch level – available also for projects with multiple phases

Learn more about new features in SIMCA 18 What's New.pdf included in the delivery package.

Since this version fixes many customer reported issues, we recommend you use SIMCA 18 even if you use SIMCA-online 16 or 17 versions. Learn more below, under Compatibility.

Trial version

A Trial version can be installed on a physical PC and runs for 30 days. After that, you need to activate a license to continue using it.

Obtaining a SIMCA 18 license

If you have a valid subscription or maintenance you are entitled to this upgrade, and it is automatically available in your My Sartorius account.

To purchase SIMCA 18, contact your sales representative, Contact us. After purchase you'll receive a delivery email with instructions on how to activate the license. Save a copy of the email as you might need it later if you reinstall the product or want to change the license. Learn more about licensing below.

Download

Download the trial software from the SIMCA product page.
Download released versions from My Sartorius after you have obtained a license.

Installation

Installation and activation are described in the ReadMe and Installation Guide.pdf in the downloaded zip. SIMCA runs on all modern PCs. See System requirements below.

About licensing

SIMCA needs a license to be functional after the 30 day Trial has expired.

The license specifies the available features in SIMCA and may also contain an expiry date after which the software stops working.

A PC with SIMCA can be licensed in three ways;

By providing an Activation ID and activating over the internet (or with an offline procedure). The same Activation ID may allow one or more activations.
Using an on-premises License Server that your organization manages. The license server assigns the license to SIMCA (an Activation ID is not used in SIMCA in this case). License usage is tracked by the license server.
Using a manually created license file provided by Sartorius. This is a rarely used fallback solution.

Learn about the license and manage it in SIMCA in File | Help. Contact your sales representative with any license questions.

Compatibility with earlier versions

SIMCA 18 saves project files in a forward compatible file format when no new functionality is used. This makes most project files compatible with previous releases of SIMCA-online, SIMCA-Q and SIMCA, even though you use the latest SIMCA 18 release to work with the project.

Features that require at least SIMCA 17 format are:

MovingAverage, AsLSBaselineCorrection, AsLSSmoothing, BaselineCorrectionLinear, BaselineCorrectionPeak, PeakHeightNormalization, PeakAreaNormalization
Derivatives and Savitzky-Golay with derivative order of Quartic or Quintic
EWMA with Symmetric weighting (which is now the default since SIMCA 17)

Features that require SIMCA 18 format are:

PCA steady state batch evolution models
Models with calibration transfer
Generated variables using qualitative variables

Release date

The version of this release is 18.0.0.372. Release date 2023-04-03.

Validation

SIMCA has been fully validated. The validation report and the full validation package are available on the SIMCA product page. To unzip the validation zip you need a password which you get from your sales representative.

System requirements

SIMCA runs on all modern PCs.

Any x64 computer hardware supported by Windows
Supported versions of Windows 11 or Windows 10, Microsoft Windows Server 2022, 2019, 2016 or 2012 R2.
Microsoft .NET Framework 4.6.2 or later. The latest 4.8 version is recommended.
700 MB available hard disk space for a full installation.