Concentration of Biologics with Vivaflow® SU to Support Formulation Development Application Note
Authors: Michaela Kreiner, Gavin W Halbert, John S Cashman | Last updated: May 2024
Overview
Biological therapies are designed to target specific molecules or pathways in the body for precise and effective treatment of diseases such as cancer. When developing novel biologics, formulation development is a critical part of the process, to ensure safety, stability, and commercial viability. During formulation development, ultrafiltration is an invaluable technique to increase the concentration of dilute biologics from bulk material. In this study, Vivaflow® SU tangential flow filtration (TFF) cassettes were tested in a formulation development workflow and evaluated for concentration performance.
- Document type: Application note
- Page count: 5
- Read time: 6 minutes
Key Takeaways
- Understand the importance of ultrafiltration for bulk material concentration
- See how lab-scale TFF with Vivaflow® SU enables effective concentration of biologics
- Discover the importance of testing multiple membranes for process optimization
- Learn how Vivaflow® SU ensures efficiency and sample integrity in formulation development
This Resource is Designed for:
- Formulation development scientists
- Process development scientists
- Research scientists
Applications Supported:
- Formulation development
- Tangential flow filtration
- Ultrafiltration
