Technical Note: Automatically Detect and Manage Clogs on iQue®
Last updated: November 2025
Overview
Log that Clog: Automatically Detect and Manage Clogs on the iQue® High-Throughput Screening (HTS) by Cytometry Platform
Flow cytometers are designed to interrogate the features of individual cells through the precise presentation of single cells in a fluid suspension passing through a flow cell. Due to this intrinsic configuration of the instrument, the technique is particularly susceptible to cellular and particulate aggregation, which can cause clogging of the flow cell and lead to catastrophic effects on data capture.
Unlike other cytometers, the iQue® High-Throughput Screening (HTS) by Cytometry Platform, uses an innovative sampling method, reliant on air gaps to separate samples. This document provides technical information on the clog detection and management feature of the iQue® 5 HTS Platform.
- Document type: Technical Note
- Page count: 9
- Read time: 9 minutes
Key Takeaways
- Recognizing a Clog
- The iQue® 5 Bubble Sensor
- iQue® 5 Clog Detection Features
- Case Study Data
- Instrumentation Practices
