eBook, The Science of Transformation: Exploring CAR-T, iPSC Differentiation, and Gene Delivery
Last updated: June 2025
Overview
This eBook explores advancements in cell therapy, focusing on CAR-T cells, iPSC differentiation, and gene delivery. The rapid development of CAR-T therapies in immuno-oncology is highlighted. Despite clinical successes, challenges such as high costs, technical difficulties, and patient variability remain.
Manufacturing processes, cellular assessment, phenotypic characterization and functional profiling of CAR-T cells, using platforms such as iQue® High-Throughput Screening (HTS) by Cytometry and Incucyte® Live-Cell Analysis, are discussed.
- Document type: eBook
- Page count: 31
- Read time: 70 minutes
Key Takeaways
- Phenotypic and functional characterization of CAR-T cells
- Challenges and solutions in CAR-T discovery and development
- Optimizing human hepatic organoid development
- Optimizing advanced cell models
- High-throughput screening and characterization of lipid nanoparticle (LNP) formulations for nucleic acid delivery
- Recommendations for high parameter flow cytometry assay development to understand cell therapy products
