HTVS-Raman for Process Monitoring in Downstream Bioprocessing


Raman technology can be extremely valuable for real-time monitoring in downstream bioprocesses. Raman spectroscopy allows for effective and reliable monitoring of materials such as monoclonal antibodies, thus enabling purification efficiency. The use of Raman spectroscopy allows molecular characterization of proteins and other materials eluting from a separation unit, which in turn provides specific actionable information to optimize the downstream operations critical to the purification process. This webinar will demonstrate the selective quantification of 2 distinct proteins post-capture column, which is used to demonstrate breakthrough monitoring. The HTVS™ technology exclusively employed in Tornado Raman spectrometers, such as the Hyperflux™ PRO Plus and the Process Guardian™ Raman, enable the speed of detection critical for these downstream measurements


What You Will Learn:

  1. Understand how Raman technology can be used for real-time monitoring in downstream bioprocesses
  2. See how Raman spectroscopy allows molecular characterization of proteins eluting from a separation unit
  3. Learn how Raman spectral data can be used in breakthrough monitoring

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Presenter


The webinar is presented by Shaun Fraser, who is an Applications Manager for Raman Process Analytical Technology at Tornado Spectral Systems – A Bruker Company. He has several years of experience in applying Raman spectroscopy to the biotechnology space and has a passion for advancing technologies in the field. Shaun holds a master’s degree in chemical and biochemical engineering from the University of Western Ontario.