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High-Throughput Media Optimization for CHO Cell Lines
To speed up media optimization, manufacturers can use the statistical design of experiments and multiplexed cell cultivations in microtiter plates or scale-down model bioreactors. But it can be challenging: —
- Media can contain more than 50 different compounds
- Modifying basal media and feeds and performing multiple iterations is often required.
- A methodology that combines data-rich experiments with advanced data analytics can help overcome these challenges