Advanced Materials & Processing
A global multidisciplinary Sartorius team of polymer chemists, material scientists, biochemists, engineers, and IT specialists tackles a broad range of topics to identify dynamic innovations for next-generation technologies and application fields for life sciences and biopharma. Our goal is to create concepts for personalized plug-and-play approaches for any molecule or modality, enabling right-first-time process development with predicted manufacturing ability using simplified lower-cost solutions. New technologies and approaches are evaluated and researched for feasibility and that will ultimately transition into the biopharma domain.
“Working together to tackle the tough challenges of today, is an exciting opportunity to influence the industry towards, expanding patient global access to the novel biological modalities of tomorrow.”
David Pollard, Head of Advanced Materials & Processing
A key focus is partnering with external collaborators, including academic institutions, pharma companies, start-ups, and technology providers. Examples of research areas comprise creating closed bioprocessing concepts via the use of novel plastics and additive manufacturing that will enable the seamless aseptic transfer from vial to production. We are creating new bioprocessing concepts of intensified and integrated approaches to enable smaller footprint, flexible and lower-cost bioprocessing. The concepts are designed with a plug-and-play toolbox to provide flexibility for multiple modalities such as mAbs and cell/gene therapies.
Robustness and efficiency will be improved through the application of advanced control strategies and sensorics for autonomous operations, including product attribute control and real-time release. Research & Development (R&D) throughput will be enhanced by the research of miniaturization tools to generate large data sets to support prediction and simulation models. These new concepts are designed with sustainable approaches to supporting the plastics circular economy, including chemical recycling concepts and research towards biosourced/biodegradable plastics. Our workflow concepts for the digitalization of R&D through to production include approaches for the ease of equipment connectivity, unified data handling, tools to ease advanced human interaction and assisted decision-making workflows.