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Scalable EV purification with membrane chromatography
Extracellular vesicles are a rapidly growing therapeutic modality, but commercial translation is limited by the lack of robust, scalable downstream purification technologies. This application note demonstrates how Sartobind Convec® D membrane chromatography enables efficient depletion of non-vesicular extracellular particles while maintaining high EV recovery, structural integrity, and bioactivity.
Key learning objectives:
- Understand the downstream barriers limiting EV commercial translation
- See how Sartobind Convec® D membranes support EV recovery and impurity clearance
- Explore orthogonal analytics for assessing EV purity, integrity, and bioactivity
- Review scale-up data supporting predictable EV purification performance
