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Assuring the Multipotency of Your Human Mesenchymal Stem Cells
Human MSCs (hMSCs) help scientists study many diseases, but they come with challenges. They’re found in small quantities in situ, they’re hard to isolate, and they can contain other off-target cell types.
Scientists need to purify and expand hMSCs in vitro to harvest enough quantities for experiments, but increasing passages will reduce differentiation potential and genomic integrity. Using the right method with a high-performance culture medium is key to high quality and reproducibility.