Publications Review: Advanced Flow Cytometry Applications in Antibody Discovery, Engineering and Development

Overview

The unique ability of antibodies to bind to antigens, with high affinity and specificity, makes them invaluable tools in the diagnosis and treatment of diseases, including cancer and infectious diseases.

The versatility and complexity of flow cytometry plays a crucial role in antibody screening and cell phenotyping.  For example, the identification of antibody producing cells, the elucidation of binding specificity of candidate antibodies and the evaluation of the functional effects of candidate antibodies, such as their ability to induce cell death.

In addressing the growing need for streamlined, high-throughput solutions in this space, the iQue^® Advanced Flow Cytometry Platform stands out. Designed for efficiency, the iQue^® platform’s user-friendly operation, multiplexing, rapid measurements and the fastest sample acquisition speed, integrate seamlessly with current screening workflows.  Therefore optimizing selection processes, and ensuring that the most promising antibodies are prioritized for further development.

In this publications review, we highlight the capabilities of the iQue^® platform, in advancing this critical field of antibody discovery and development, in the areas of infectious diseases, neurological disorders, cancer, and more.

• Document type: Publications Review
• Page count: 8
• Read time: 18 minutes

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