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Comparability Study of an Ion Exchange Monolith and Affinity Resin for the Purification of AAV8

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Comparability Study of an Ion Exchange Monolith and Affinity Resin for the Purification of AAV8

AAV purification can be challenging – complexity can affect separation efficiency, and affinity elution can introduce impurities. 

This poster explores how to optimize AAV downstream. Learn the advantages of using an ion exchange monolith versus affinity column, and how you can enhance recovery, purity, and processing efficiency. 


  1. Learn how a monolith-based anion chromatography column increases available doses by 30%. 
  2. Compare the efficiency of different capture step methods at reducing impurities. 
  3. See how much time you can save using monolith-based columns compared to affinity columns. 

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