Article: How to Achieve Pharmacopeia-Compliant Bioburden Testing of Viscous Samples
Authors: Dr. Nils Jäger, Sartorius Lab Instruments; Juliane Grossmann, Sartorius Lab Instruments | Published by: rapid microbiology | Last updated: Jan 2024
Overview
This article addresses the challenges and solutions for bioburden testing of viscous non-sterile products in compliance with pharmacopeial standards. It discusses the impact of viscosity on microbial mobility and filtration analysis, and outlines strategies for sample preparation to ensure accurate microbiological results. Insights from Nils Jäger, Application Scientist, and Juliane Grossmann, Product Manager at Sartorius Lab Instruments, are provided to guide laboratories in handling difficult applications.
- Document type: Article
- Page count: 4
- Read time: 6 minutes
Key Takeaways
- Viscosity's impact on bioburden testing requires protocol adjustments, such as sample heating or dilution, to ensure accurate membrane filtration.
- Expert guidance is essential for handling viscous samples, with specific pharmacopeial procedures needed to maintain testing integrity.
- The Microsart® filtration system offers a tailored solution for viscous samples, with sterile, chemically compatible units that streamline the testing process.
This Resource is Designed for:
- Lab Managers
- Microbiology Managers for Pharma QC
- Microbiology Managers for Personal Care
- Lab Technicians
Applications Supported:
- Quality Control
- Microbial enumeration
- Filtration of Viscous and Oily Samples
- Filtration of Products for Personal Care
Figure 1. Cover of Article