An Efficient End-to-End AAV8 Platform Process at 50 L Scale Using Sartorius Technology

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An Efficient End-to-End AAV8 Platform Process at 50 L Scale Using Sartorius Technology

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An Efficient End-to-End AAV8 Platform Process at 50 L Scale Using Sartorius Technology

Discover how Sartorius and Matica Biotechnology streamlined AAV8 production at 50 L scale with single-use technologies — achieving high recovery, efficient impurity removal, and >3x enrichment of full capsids.

Key Learning Objectives:

Understand upstream AAV8 production using stirred-tank bioreactors
Explore clarification and TFF strategies for high recovery and purity
Learn chromatography methods for capture and polishing
See how full vs. empty capsids were effectively separated
Recognize the scalability and flexibility of single-use platforms

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An Efficient End-to-End AAV8 Platform Process at 50 L Scale Using Sartorius Technology

An Efficient End-to-End AAV8 Platform Process at 50 L Scale Using Sartorius Technology

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