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Computational Fluid Dynamics for Enhancing Dissolution Applications in Biopharmaceutical Manufacturing
CFD with M-Star (MStar-CFD) simulates powder dissolution to accelerate buffer/media prep and de-risk scale-up in single-use mixers. Predictions validated from 50–1,000 L show rapid, reproducible mixing.
Key Takeaways:
- Hydrodynamics & dissolution modeled; aligned to pH/conductivity data
- Fast, uniform mixing in Flexsafe Pro Mixer
- Reproducible times and buffer properties; guidance for scale-up