Combining S-MCC With Sartobind® Rapid A: A Proof of Concept From PD to Pilot Scale

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Combining S-MCC With Sartobind^® Rapid A: A Proof of Concept From PD to Pilot Scale

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Combining S-MCC With Sartobind^® Rapid A: A Proof of Concept From PD to Pilot Scale

This application note presents a proof-of-concept study evaluating the use of Sartobind^® Rapid A membranes in sequential multi-column chromatography (S-MCC) for monoclonal antibody capture. It demonstrates successful scale-up from process development to pilot scale, maintaining yield and purity while reducing buffer consumption and enabling process intensification.

Key Takeaways:

Explore how S-MCC improves process efficiency compared to rapid cycling chromatography.
Learn key parameters for scaling Sartobind^® Rapid A from lab to pilot systems.
Review process data supporting yield, purity, and cost reduction at both scales.

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Combining S-MCC With Sartobind® Rapid A: A Proof of Concept From PD to Pilot Scale

Combining S-MCC With Sartobind® Rapid A: A Proof of Concept From PD to Pilot Scale

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Combining S-MCC With Sartobind^® Rapid A: A Proof of Concept From PD to Pilot Scale

Combining S-MCC With Sartobind^® Rapid A: A Proof of Concept From PD to Pilot Scale