CIMmultus^® QA HR Columns: Ensuring Consistency, Scalability, and Purity  

This application note demonstrates an advanced AAV E/F separation using CIMmultus^® QA HR. Coupled with an improved chromatographic method, this solution delivers reliable AAV purification and elevates downstream robustness to meet industrial manufacturing demands.

CIMmultus^® QA HR line enables consistent full-capsid enrichment and purity, even when using step gradient. Available from 1 mL to 8 L, CIMmultus^® QA HR supports seamless lab-to-manufacturing scalability with reproducible performance at every scale. Released under stringent QC based on empty AAV elution conductivity, these monolithic chromatography columns ensure highly reproducible performance across all column scales and batches.