Using batch and fed-batch approaches and the support of at-line analytical tools, IVT reactions can produce mRNA reaching 12g/L. We demonstrated how to achieve high recovery and quality using the Hydrosart TFF cassette and our Sartopore 2 for sterile filtration.
What Will You Learn:
Rok Sekirnik graduated with a degree in chemistry from the University of Oxford, where he also completed his PhD. His team at BIA Separations, now a Sartorius company, focuses on developing high-yielding, cost-effective purification approaches for pDNA and mRNA production.
Marc Noverraz joined Sartorius in 2021 as a Process Technology Manager for separation technologies. He earned a master’s degree in chemical engineering from EPFL in Lausanne, Switzerland.
At Sartorius, his work focuses on downstream processing of new modalities and how to fit Sartorius technologies into processes like AAV, lentivirus, and mRNA.
Optimize your IVT reactions to take your mRNA process to the next level. Discover how in our on-demand webinar.
