Webinar: Integrated Platform for Intelligent Upstream Process Intensification

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Integrated Platform for Scalable, Flexible and Intelligent Upstream Process Intensification

The Biopharma industry is challenged by costs pressures, increasing numbers of low volume products with unpredictable demand and the advent of new less stable molecules, like bi-and multi-specifics that may not always be suitable for production in the standard Fed-Batch platforms.

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Flexible, Single-Use manufacturing plants, in combination with process intensification strategies, can deal with these multi-product, multi-modality portfolios and pipelines and are becoming a central part of biomanufacturers’ production infrastructure.

Watch this webinar and learn more about the Sartorius toolbox for the development and implementation of intensified upstream processes, including a cell line generation service, the high-throughput perfusion system Ambr®, integrated PAT and software tools combined with commercial scale bioreactors with perfusion capabilities.

Key Learning Objectives

  1. Find out how Upstream Process Intensification helps with increase in productivity
  2. What different types of Upstream Intensification processes brings to the table
  3. How the selection of the right clone and PD development at an early stage can help with scale-up and achieving the required process performance
  4. Find out why versatile options in seed train for manufacturing can fulfill the needs for lower COGs and higher flexibility

Meet Our Expert

Gerben Zijlstra

Manager of Process Technology Consultants, Segment Marketing Proteins

Gerben received his Ph.D. on cell culture process intensification from the Wageningen University (NL). He has worked for over 20 years in the industry on Biological product and process development, as well as innovation projects. As an early adopter of Single-Use technology and Process Intensification he has invented Concentrated Fed-Batch technology, licensed by e.g. Amgen, and has worked on several Continuous BioManufacturing and Gene Therapy projects. Since the end of 2016 Gerben works for Sartorius as Manager of Process Technology Consultants for Intensified and Continuous BioManufacturing.

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