Webinar: How to Intensify Upstream Process Development With Ambr® 15 & 250

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How to Intensify Upstream Process Development With Ambr® 15 & 250

PD teams want to intensify upstream processes and ensure results translate to manufacturing scale. Perfusion processes may be the answer but defining/optimizing these workflows takes time and money.

This webinar draws upon real-world evidence to show how Ambr® 15 & 250 support clone selection, media/feed screening and process parameter optimization in perfusion mimic and full perfusion conditions, fast-tracking intensified cell culture processes. 

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Key Learning Objectives

  1. See how the high throughput capabilities of Ambr® maximize the potential of upstream intensification

  2. Explore the different modes of intensification that Ambr® technology supports perfusion mimic; Alternating Tangential Flow (ATF); and Tangential Flow Filtration (TFF)

  3. Assess the real-world impact of Ambr® through case studies showing the performance in high-throughput, intensified PD

Meet Our Experts

James Edwards

Development Scientist, Cell Culture Technologies, Sartorius

James Edwards is a Product Development Scientist for automated Cell Culture Technologies at Sartorius. He was the primary cell culture scientist working on the development of the Ambr® 250 high throughput perfusion system and was responsible for demonstrating the performance of the system for intensified cell culture activities. In addition to supporting existing Ambr® systems, he contributes to the development of new automated bioprocess products.

Prior to working at Sartorius, James lectured Biological Sciences at Bournemouth University, UK and researched DNA repair and epigenetics at the University of Southampton, UK.

Donald Traul

Senior Field Application Specialist, Sartorius North America

As a Senior Field Application Specialist with Sartorius North America, Don Traul is readily available to provide in-depth knowledge of all products from the Ambr® portfolio to customers across the continent.

Since the launch of the first Ambr® 15 cell culture system in 2010, Don has made significant contributions to Ambr® product development, thanks in part to his expertise in molecular neurovirology, early upstream cell line and process development, as well as recombinant viral vector production.

Don received bachelor’s degrees in biology and chemistry from St. Olaf College. He went on to earn his master’s degree in Clinical Laboratory Science at the University of Wisconsin and then completed his Ph.D. in Microbiology at Colorado State University.

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