Webinar Re-Imagine mAb Purification: Discover the Power of Membranes |Sartorius

On-Demand Webinar | Re-Imagine mAb Purification: Discover the Power of Membranes

We are pleased to invite you to our webinar during which Sanket Jadhav (Process Technology Manager, Sartorius) and Abijar Bhori (General Manager, Process Development, Enzene) will share process development strategies for building a fully membrane based chromatography platform and its benefits in mAb purification.

Resin-based monoclonal antibody (mAb) purification is slow, expensive, and complex to set up, representing a significant productivity bottleneck. In this webinar, we introduce a new, fully membrane-based platform for faster and more flexible mAb purification.

Sartobind^® Rapid A membranes are ready-to-use replacements for Protein A resins. Their entire lifetime can be used within a single batch or campaign, achieving >10x higher cycle productivity. Polishing with Sartobind^® membranes enables higher loading at high flow rates, further boosting productivity. Membranes eliminate the need for packing | unpacking, cleaning validation, and cold storage required for columns, reducing the overall manufacturing footprint. They are also available in a variety of chemistries, making them suitable for removing a range of impurities. The results demonstrate that an end-to-end membrane-based process can support fast, hassle-free, flexible, economical, and more sustainable mAb manufacturing.

What You Will Learn:

Learn how to intensify your mAb capture step to achieve higher productivity
Explore how to implement membranes for efficient and fast polishing
Navigate the design of a fully membrane-based process for time and cost savings

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Abijar Bhori

Sr. General Manager, Head of Purification Process Development, Enzene

Abijar is currently heading Purification Process Development and Drug Product Development functions at R&D division of Enzene Biosciences Ltd., Pune (a fully owned subsidiary of Alkem Laboratories Ltd.). He has around 21 years of experience in downstream process development of therapeutic products. He has extensive experience in small and large biomolecule purification process development, fully connected continuous manufacturing (FCCM) process development (EnzeneX™), process intensification, scale-up, scale-down model development, technology transfer, non-infringing formulation development, and device development (pen and auto-injector). He holds an M.Sc. (Technology) in Bioprocess Technology from the Institute of Chemical Technology (formerly UDCT), Mumbai.

Sanket Jadhav, PhD

Process Technology Manager

Sanket is a Process Technology Manager at Sartorius, leading various customer collaborations as a project technical lead and project manager. Sanket started his career as a process engineer at Biocon in Bangalore, India, where he led projects on process design, production, and facility design for insulin. Sanket earned his PhD in Chemical Engineering in Australia and then moved to the Netherlands, where he led consulting projects in designing tools for SMB systems, optimizing processes and facilities, establishing USP perfusion processes, and troubleshooting end-to-end processes for customers in Europe and the USA. With >12 years of biopharmaceutical research and industrial experience, Sanket has a penchant for developing cost-effective, sustainable, and intensified platform technologies for modalities like proteins, mRNA, and other gene therapy applications.