On Demand Webinar Maximizing Manufacturing Productivity with a Continuous Chromatography Process

Webinar | Maximizing Manufacturing Productivity with a Continuous Chromatography Process

Biologics manufacturers are under increasing pressure to reduce production costs. This is a key driver for moving to continuous processing, which maximizes productivity while minimizing footprint. Since its inception, Just-Evotec Biologics, Inc. has explored the use of continuous processing to reduce the cost of manufacturing biologics. One part of Just-Evotec Biologics’ strategy is a modular facility design that supports seamless scaling between early and late-phase productions. Another cornerstone is the process itself: Continuously perfused bioreactors are coupled with a multi-column capture step and alternating two-tank viral inactivation, enabling high mass output and enhanced product quality. The coupling of these downstream steps directly to the perfused bioreactor effluent enables efficient liquid handling of large volumes with minimal operator intervention.

In this GEN webinar, our speaker, Andrew Wagner, PhD, delves into Just-Evotec Biologics’ strategy for continuous processing. Discover their approach, featuring a modular facility design and an integrated, continuous purification process, confirming that today's technology can deliver highly productive processes.

What You Will Learn:

How multi-column continuous capture improves efficiency and reduces resin utilization
How coupling viral inactivation with multi-column capture streamlines liquid handling
To understand the challenges to achieving fully end-to-end continuous manufacturing

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Andrew Wagner, PhD

Senior Scientist II Purification Process Design, Just-Evotech Biologics

Andrew Wagner is a Senior Scientist II in Purification Process Design at Just – Evotec Biologics, where he supports purification process development to advance low-cost biotherapeutics manufacturing. Andrew has been with Just-Evotec since 2020. He started his career at Grace Bio-Labs, where he developed processes for a protein microarray technology platform.

Andrew received his PhD in Biochemistry from the University of Oregon, where he gained experience in protein purification and single-molecule fluorescence microscopy. His interest in science began at Colorado College, where he earned a BA in Chemistry and Biochemistry studying host-parasite interactions of the ponderosa pine. In his free time, you can find Andrew running, exploring the mountains of the PNW, and foraging for mushrooms and huckleberries.