B1 - Crossflow Filtration Part 1

Target group: Technicians and scientists with or without previous knowledge in the field of crossflow filtration.

This course is designed to provide you with state-of-the-art knowledge about the use of crossflow filtration in the biopharmaceutical industry. It consists of two different parts which can be booked separately.

In Part 1 we will focus on the fundamentals of crossflow filtration and how to optimize crossflow filtration parameters for concentration and diafiltration.

Theoretical aspects include:

• Crossflow filtration theory
• Membrane characterization | membrane selection
• Factors influencing performance
• Operating conditions
• Cleaning-in-place (CIP)
• Applications in biotechnology

Practical exercises:

• Operational set-up of the systems
• Determination of clean water flux
• Cell retention by microfiltration (model solution)
• Concentration of a protein solution by ultrafiltration
• Removal of low-molecular weight contaminants by diafiltration
• Cleaning

Related topics and additional seminars: B2 Crossflow Filtration Part 2
There are no special classes reqiured for this seminar