Cubis® III Lab Balances - Made to Connect to Your Lab
Direct Integration and Built-in Compliance — No Middleware, No Hidden Costs.
Since its introduction in 2009, the Cubis® balance family has set the benchmark for premium laboratory weighing — the choice of scientists and quality professionals who cannot compromise on data integrity or regulatory compliance.
Each generation has redefined what a balance can deliver, combining exceptional metrological performance with the connectivity, intelligence, and vision that Lab 4.0 demands. Cubis® III sets a new standard for straightforward, transparent, and direct integration as well as built-in compliance: No Middleware, No Hidden Costs.
What you can expect from day one:
- Uncompromising accuracy: Best‑in‑class weighing performance delivering precise, reliable results.
- Direct connectivity: Connect seamlessly to any open digital ecosystem.
- Build-in compliance: Two variants: Cubis® III for non-regulated labs and Cubis® III Max for regulated environments
- Scalable design: Start with one instrument, then replicate configurations to build a connected, compliant fleet.
Cubis® III Weighing Portfolio
Two Packages – One Performance Standard
Choose the right fit for your lab. All balances are available as Cubis® III or Cubis® III Max, tailored to different needs. Both packages deliver the same class-leading weighing performance; the difference lies in the level of compliance and integration support your lab requires. You can upgrade to Cubis® III Max at any time as your requirements evolve.
Cubis® III — Standalone Optimized
Best-in-class weighing performance with powerful standalone operation
Delivers precise, reliable weighing with full process control
Versatile documentation options from print to digital
Built-in user management with convenient RFID-based, one-tap login
Safeguards weighing through guided workflows and verified calibration
Start right, scale when ready
Digital-driven performance: Top-tier accuracy and trusted reliability, ready to use out of the box
Designed for non-regulated labs: Ideal for labs that demand precise and secure weighing — no compliance burden, no added complexity
Future-ready: Expandable compliance features and advanced connectivity options as needed
Accuracy first. Compliance when ready.
Choose if you need uncompromising accuracy with straightforward operation and the flexibility to add compliance and connectivity later.
Cubis® III Max — Integration Optimized
Best-in-class weighing performance built for connected, regulated laboratories
Engineered for the most demanding regulated environments in pharma, medtech, and beyond
Comprehensive connectivity — from simple result transfer to full system integration
Enables automation of complex workflows directly on the balance
Built for seamless global deployment across sites with minimal IT effort
Enterprise Compliance & Scale
Beyond hardware: Delivers a compliant end-to-end solution without additional middleware from secure data generation to seamless integration
More than just connectivity: Ideal for digitally advanced organizations that demand full compliance, automated workflows, and enterprise-grade connectivity
Compliance built in & connected from day one.
Choose if you need validated processes, centralized control, and automated data flows across multiple sites or systems.
Cubis® III - Native Connectivity, Compliant, Middleware-Free
The Cubis® III lab balance portfolio delivers best in class weighing with full data governance—without hidden middleware costs—by connecting natively to your digital ecosystem and simplifying integration from day one. Native connectivity with embedded OPC UA enables real time LIMS/MES/ERP links; prebuilt connectors to LIMS/ELN/CDS. Supports HTTPS/FTPS/SMB, SICS/SBI, RS232/USB/Ethernet/Wi-Fi, plus TXT/CSV/PDF exports enabling compliant electronic documentation out of the box.
Cubis® III Max delivers turnkey compliance for regulated performance driven labs by consolidating everything needed for audit ready operation into a single, standalone solution—no extra software or middleware required. Native 21 CFR Part 11 features include a secure audit trail, tamper evident records with metadata, integrated electronic signatures, and comprehensive, configurable user and role management that scales with your policies and workflows. It also supports RFID login, LDAP directory integration, and automatic NTP time synchronization. The system complies with USP and major pharmacopeias (Ph.Eur., JP, ChP) and enforces minimum weight. Enterprise grade protocols reduce cybersecurity risk. The Cleaning QApp guides SOP aligned cleaning with electronic sign off for complete traceability and audit readiness.
Cubis® III integrates directly with your lab IT—or runs standalone. This eliminates middleware, extra licenses, and complex infrastructure, reducing total cost of ownership across the lifecycle. It delivers accurate results with minimal sample quantities, reducing spend on costly materials and supporting sustainability. Modular hardware and software let you configure and expand over time, keeping full control of your investment.
A single, consistent touchscreen interface across all Cubis® III and Cubis® III Max configurations streamlines training and validation, keeps SOPs consistent, and scales from a single bench to enterprise deployments. The role aware UI surfaces relevant tasks and methods, guiding users with QApp workflows, on screen prompts, and electronic signatures for 21 CFR Part 11 compliance. Built in support for RFID login, LDAP directory integration, and NTP time synchronization ensures secure access and reliable timestamps, while clear status indicators highlight readiness, minimum weight enforcement, and connectivity at a glance. With the same display platform on every balance, updates, documentation, and support are simplified—reducing total cost of ownership and delivering a uniform user experience across your fleet.
Applications for Cubis® III Lab Balances
Pharma Compliant Weighing
Complying with regulatory requirements is the highest guarantee for product safety, efficacy and process efficiency in pharmaceutical industries. See how Cubis® III balances offer high performance, meet your regulatory requirements and support safe workflow management during your daily weighing processes.
Infusion Pump Testing & Micro-Flow Calibration
Ultra-high resolution weighing for accurate flow rate assessment and regulatory compliance. The Cubis® III balances are engineered to support accurate dose administration for devices like infusion pumps, supporting your experts in product development, quality assurance, regulatory affairs, and more.
Medical Device Quality Control
Precision weighing balances for drug eluting stents for accurate, reliable results and increased productivity. Cubis® III balances increase throughput of your stent weighing, while providing premium precision.
Chemical & Consumer Care
Organic impurities can arise during the manufacturing process and/or storage of a product. Sample preparation is a key step used to identify these process-related impurities. Cubis® III premium ultra-micro | micro and high-capacity micro balances are ideal for sample preparation for analytical applications that require very small sample quantities (e.g., elemental analysis).
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Frequently Asked Questions
Product overview
Cubis® III is a high performance laboratory balance designed for teams that demand uncompromising accuracy without the complexity of regulated workflows. It delivers best in class weighing performance, supported by intuitive, safe operation and versatile documentation options from print to digital. Built in user management—including convenient RFID login—helps standardize use and protect data. When your requirements grow, the platform is future ready, allowing you to expand with compliance features and advanced connectivity. Choose Cubis® III balances for precise, reliable results in research, quality control, and routine lab work.
Cubis® III Max is Sartorius’ enterprise grade precise balance family for regulated laboratories. It combines best in class weighing performance with comprehensive connectivity to automate complex workflows and integrate across enterprise systems. Designed for pharma, medical technology (MedTech), and other highly regulated environments, it delivers secure, compliant, end to end data management without additional middleware and supports seamless global deployment with minimal IT effort. Cubis® III Max is a model variant adding features such as direct LIMS/ELN/CDS connectors that reduce interface maintenance, standalone 21 CFR Part 11 (audit trail, user management, complete metadata records, e-signatures), LDAP-based access control, and USP/Ph.Eur./JP/ChP compliance with minimum-weight enforcement—and adds guided cleaning workflows for enhanced SOP (Standard Operating Procedure) compliance.
Cubis® III is a next-generation laboratory balance family from Sartorius optimized for non regulated environments, delivering best in class weighing performance with intuitive operation, versatile documentation, built in user management, and digital guidance for tasks like cleaning and calibration, while remaining future ready so you can add compliance features and connectivity as needs evolve. Cubis® III Max, by contrast, is designed for regulated labs offering comprehensive, enterprise grade connectivity to automate complex workflows, seamless global deployment with minimal IT effort, and an end to end compliant data solution that generates secure, audit ready records without additional middleware. Both deliver the same exceptional weighing accuracy and reliability with reduced total cost of ownership (TCO).
Choose Cubis® III if you run non regulated or lightly controlled labs (e.g., R&D, academia, routine QC) and want best in class precision and accuracy with simple, standalone operation, versatile documentation, built in user management (RFID login), and the flexibility to add compliance and connectivity later.
Choose Cubis® III Max if you operate in regulated (GxP) environments like pharma or medtech and need end to end compliance with secure, audit ready data, enterprise grade connectivity to automate complex workflows and integrate with systems, and seamless multi site/global deployment without additional middleware.
Both deliver the same top tier weighing accuracy—the choice hinges on your compliance and connectivity requirements.
Cubis® III Max includes the same core capabilities and best in class weighing performance as Cubis® III and then adds enterprise grade features for regulated environments—end to end compliant, secure data generation, comprehensive connectivity for system integration, workflow automation, and seamless multi site deployment.
Connectivity and IT integration
Cubis® III provides direct, real-time data exchange to laboratory systems—LIMS (Laboratory Information Management System), ELN (Electronic Lab Notebook), and CDS (Chromatography Data System)—via an embedded OPC UA (Open Platform Communications Unified Architecture) server and standard interfaces.
No. Cubis® III offers built-in connectivity and does not require additional middleware in typical deployments, reducing integration complexity and costs.
Cubis® III supports RS232, USB, Ethernet, and Wi‑Fi for flexible device and network connectivity.
Yes. Cubis® III supports LDAP (Lightweight Directory Access Protocol) integration for centralized user and role management across regulated environments.
An embedded OPC UA server enables seamless, real-time bidirectional data exchange with lab informatics systems (LIMS/ELN/CDS).
Yes. Cubis® III offers extensive compatibility with varied IT environments through standard protocols and interfaces, enabling broad, direct connectivity.
Compliance, security, and data integrity
Cubis® III does not offer this feature, but Cubis® III Max does provide out of the box 21 CFR Part 11; end to end, audit ready Part 11 compliance with secure data generation and no additional middleware needed.
Cubis® III ensures data integrity by combining real-time weighing data transfer, reliable timestamps via integrated NTP (Network Time Protocol) synchronization, and controlled user access with audit-readiness.
Cubis® III Max is designed for regulated labs and helps meet stringent data governance and compliance expectations (e.g., 21 CFR Part 11 and global pharmacopeia standards).
Yes. Cubis® III complies with USP and other major global pharmacopeia standards (Ph.Eur., JP, ChP) and intelligently enforces critical requirements such as minimum weight to help ensure consistent, compliant weighing workflows.
Cubis® III removes time discrepancies by automatically synchronizing system time via integrated NTP (Network Time Protocol) synchronization -ensuring reliable and consistent timestamps across records for data and events.
Cubis® III integrates with company directories via LDAP (Lightweight Directory Access Protocol) to enhance security, ensure consistent access control, and reduce administrative effort—eliminating the need for separate user accounts and passwords.
Operational efficiency, TCO, and sustainability
The Cubis® III balance family lowers TCO through built-in compliance features, direct system connectivity without middleware, reduced integration and validation effort, minimized administrative overhead, and accurate results with minimal sample use. Furthermore, Cubis® III delivers long-term value by enabling configuration and expansion of hardware and software over time, providing full control over investment decisions at purchase and beyond.
High accuracy with minimal sample requirements helps reduce material consumption and waste, supporting sustainable lab practices.
Centralized user management (via LDAP), built-in compliance controls, and direct integrations reduce routine admin tasks and validation overhead.
Use cases and lifecycle
Yes. Cubis® III is designed for configurable setups and future expansion, protecting long-term value as lab needs evolve.
Cubis® III suits non regulated or lightly controlled labs needing high precision weighing benefiting from straightforward documentation (print or digital exports), built‑in user management with RFID login, and digital guidance for consistent, safe operation (e.g., cleaning and calibration).
Ideal for:
- Daily sample and reagent preparation (standards, buffers, formulations
- Routine weighing in research and academia (teaching labs, method development, prototype work)
- Non‑regulated quality control tasks (incoming materials checks, batch spot‑tests)
Cubis® III Max is ideal for regulated, digitally advanced labs where compliance, connectivity, and automation are essential. It supports GxP pharmaceutical and medical technology QC/manufacturing environments for:
- Audit ready and traceable weighing
- Validated SOP based methods
- Automated, recipe‑based dispensing/dosing and other complex workflows
- Secure enterprise integration (LIMS/ELN/MES/ERP)
- Multi site deployments needing consistent configurations and minimal local IT effort
- ALCOA/ALCOA+ data integrity
- Inspection ready operations with user and audit trail management.