Simulation-Based Optimization of Biopharmaceutical Equipment
For the use case of a high capacitance membrane adsorber there are multiple factors which may have a decisive impact on membrane structure and performance. Join us in this insightful webinar to learn how the combination of Design of Experiments (DOE) and Computer Aided Engineering (CAE) facilitate optimization of the Sartobind® membrane adsorber.
The analysis to identify the most influencing factors was based on parametric studies, which used DOE as input. Furthermore, the extended simulation model was experimentally validated by comparing the breakthrough curves of a binding molecule determined by simulation and experiment.
The work presented in this webinar is truly encouraging pointing to several aspects to consider in the future, such as:
- Focus on simulation models that take other effects into account, such as the relationship between permeability and binding capacity
- Involve other membrane types that have more complex membrane structures
- Further product development
- General applicability of presented approach to help customers understand and optimize their own experiment and equipment
What You Will Learn:
- Learn about how DOE help navigate in a large parameter space
- Discover how CAE simulations thrive on DOE input
- Get insights into how a deep understanding of the studied system is provided by the combination of DOE and CAE