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Sartobind® S nano 3 mL, 8 mm bed height

Sartobind® S membrane adsorber units combine the advantages of convective media and ion exchange chromatography for rapid and easy contaminant removal or capture of virus and virus like particles.

Item no.:  96IEXS42EUC11--A

Availability (ex works):  On Request

   

Sartobind® S membrane adsorbers display a macro-porous structure with pore size of > 3 µm. Sulfonic acid ligands are bound covalently to the complete internal surface of the membrane, resulting in separation media of high binding capacity combined with exceptional high flow rates.

Applications:

The S membrane adsorber is successfully used in FDA-approved drug manufacture to remove host cell proteins at high flow rates. As a cation exchanger it displays not only aggregate removal capabilities but typically at least ten-fold higher binding capacity for viruses and virus-like-particles (VLP).

Benefits:

The Sartobind S adsorber speeds up the production process by high flow rate and opens new opportunities for the purification of therapeutic proteins and vaccines.

  • High speed host cell protein removal up to 30 bed volumes/ min
  • Aggregate removal

Easy to use:

  • Plug and play devices from 0.08 ml to 5 l
  • Can be used like a filter
  • Flow rate up to 30 bed volumes/min
  • Disposable or re-usable

Application Note

Sartobind® Membrane Adsorbers for Capture and Polishing
en 1.1 MB
Single-Use Membrane Chromatography in ADC Production
en 1.6 MB

Brochure

Sartobind® Membrane Chromatography
en 2.3 MB
宣传手册:实验室过滤产品精简目录
zh 19.0 MB

Datasheet

Sartobind® Q and S, 4 and 8 mm bed height
en 1.1 MB

Flyer

Sartobind® selection guide
en 1.0 MB

User Manual

Directions for Use - Sartobind® Q and S - Void Volume Optimized Capsules and Cassettes With 4 | 8 mm Bed Height
en 2.1 MB

 

  • Connectors
    Luer female connectors
  • Housing Material
    Polypropylene (PP)
  • Maximum Venting Pressure
    0.5 bar, 0.05 MPa, 7 psi
  • Membrane Adsorber Format
    Capsules
  • Membrane Area
    110 cm²
  • Membrane Material
    Stabilised reinforced cellulose
  • Membrane Type
    Strong cation exchange membrane
  • Thermal Stability
    Sartobind capsules with ion exchange membranes can be autoclaved at 121 °C for 30 min. We recommend one autoclaving cycle only.
  • Type
    Membrane adsorber
  • Typical Dynamic Binding Capacity 10% per unit
    77 mg
  • Void Volume
    4 mL

 

  • Bed Height
    8 mm
  • Bed Volume
    3 mL
  • Ligand
    Sulfonic acid
  • Ligand Density
    2 – 5 µeq/cm²
  • Materials of Construction
    • Polypropylene, polyester
    • polyester
  • Maximum Operating Pressure
    0.4 MPa
  • Pore Size
    3 – 5 µm
  • Recommended Flow Rate
    15 mL/min
  • Reference Protein
    Lysozyme
  • What you receive
    • 4 capsules
    • 2 adapters Luer male to UNF 10-32 female
    • 1 operating instruction
    • 1 certificate
  • pH Stability
    pH 3 – 14 (short term), pH 4 – 13 (long term)

 

  • Application
    • Polishing
    • Capture
  • Biosafety
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
  • Pack Size
    4