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Octet® Sialic Acid (GlyS) Kit

The Octet® Sialic Acid (GlyS) Kit is designed for a rapid high-throughput relative Sialic Acid content screening during early clone selection stages in Cell Line Development (CLD). The kit allows to conveniently screen and rank both crude and purified mAb and non-mAb protein samples.

Key Features of the Octet® Sialic Acid (GlyS) Kit

  • Designed to analyze both crude and purified samples: no enzymatic digestion or purification required
  • Relative Sialic Acid content screening and ranking of samples into groups – high, medium or low
  • High-throughput analysis of 96 samples, in parallel, in less than one hour on the Octet® RH96 system

Top Applications for the Octet® Sialic Acid (GlyS) Kit

  • High-throughput Sialic Acid content screening

Item no.:  18-5135

Price:  $1,555.00

1 Piece
 

The Octet® GlyS kit has been designed for a quick high-throughput relative Sialic acid content screening in both purified and crude cell culture samples during early clone selection stages in the CLD process. The kit can be used to screen and rank both mAb and non-mAb samples (e.g. high, medium or low) and when combined with titer analysis (which can be also performed on the Octet® platform), it facilitates the selection of the top performing cell lines producing proteins with the most favorable glycan (Sialic Acid) profile. The GlyS kit allows verified decisions to be made about which clones are the most suitable to move downstream for further optimization. Reliable glycosylation data (as a key part of Critical Quality Attribute (CQA) profile) at this early stage supports shorter CLD lead times and prevents later failures.

With the GlyS Kit, no sample purification or digestion is required. This allows for the analysis of crude samples. Now, you can screen to identify ideal candidates or failing candidates much faster and much earlier. The GlyS Kit can help reduce preparation time by up to three hours.

Simplified Assay Workflow

The Octet® GlyS Kit is based on the use of sialic acid specific lectin. It allows to analyze both crude and purified samples without the need for purification or enzymatic digestion. This essentially eliminates the need for any sample preparation beyond a dilution step, simplifying the sialic acid screening workflow for users. Additionally, the GlyS kit reduces time to results and increases analysis throughput by allowing to screen up to 96 clones in under one hour on the Octet® RH96 system.

Combine Sialylation and Titer Data on the Octet® Platform

Octet® Analysis Studio software enables effective combination of relative Sialic Acid content screening data and titer determination data (acquired on the Octet® platform) on the same sample. It allows verified decisions to be made about which clones are the most suitable to move downstream for further optimization. Reliable data at this early stage supports shorter CLD lead times and prevents later failures.

Datasheet

Octet® Sialic Acid (GlyS) Kit Datasheet
en 501.1 kB

Applications

  • Application
    Glycan Screening

Compliance Information

  • GMP Kits
    No

Features

  • Device/Instrument Compatibility
    • Octet® R2
    • Octet® R4
    • Octet® R8
    • Octet® RED96e
    • Octet® RH96
    • Octet® RH16

Product Information

  • Brand
    Octet®BLI
  • Pack Size
    1
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The Octet® Anti-CHO HCP Kit is for rapid high-throughput quantitation of residual CHO host cell proteins (HCPs) in bioprocess samples. The kit utilizes industry-standard Cygnus 3G anti-CHO HCP antibody and offers high sensitivity and broad HCP recognition. Octet® Anti-CHO HCP Kit includes 1 tray of 96 biosensors, and all calibrators, reagents, and buffers necessary to analyze 96 HCP samples. 10% Discount is included on packs of 5 kits.

Key Features of the Octet® Anti-CHO HCP Kit

  • Fully analyzed HCP results for 96 samples in one hour
  • High precision assay with 5-10% CVs
  • Detection sensitivity as low as 0.5 ng/mL

Top Applications for the Octet® Anti-CHO HCP Kit

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The Octet® Anti-CHO HCP Kit is for rapid high-throughput quantitation of residual CHO host cell proteins (HCPs) in bioprocess samples. The kit utilizes industry-standard Cygnus 3G anti-CHO HCP antibody and offers high sensitivity and broad HCP recognition. Octet® Anti-CHO HCP Kit includes 1 tray of 96 biosensors, and all calibrators, reagents, and buffers necessary to analyze 96 HCP samples. 10% Discount is included on packs of 5 kits.

Key Features of the Octet® Anti-CHO HCP Kit

  • Fully analyzed HCP results for 96 samples in one hour
  • High precision assay with 5-10% CVs
  • Detection sensitivity as low as 0.5 ng/mL

Top Applications for the Octet® Anti-CHO HCP Kit

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