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kSep® Systems

Advanced, scalable, single-use automated centrifugation systems

Sartorius kSep® systems provide robust, single-use bioprocessing solutions in the areas of recombinant therapeutics, cell therapy, vaccine manufacturing, and blood processing.

As per your process requirements, our fully-automated systems are optimized to recover supernatant or solids (cells | particles) in a continuous manner.

kSep® systems solve the problems of traditional centrifugation and filtration based technologies by handling very high cell densities while providing high recoveries and product quality.


Choose your product

Products (2)

kSep® 6000S System
kSep® 6000S System
Item no.: KSEP6000S
Cell Capacity per Cycle
(CHO) Up to 1200 Billion
Working Volume
10 – 6,000 L
kSep® 400 System
kSep® 400 System
Item no.: KSEP400
Cell Capacity per Cycle
(CHO) Up to 80 Billion
Working Volume
0.5 – 200 L

Patented kSep® systems technology is the only current technology that provides significant advantages for users that want to either harvest cells as product or discard cells as by-product during manufacturing.


Smart Bioprocessing

  • Integrates and | or reduces processing steps and time
  • Improves recoveries of both solids and liquids
  • Provides option to selectively remove small particulate impurities, e.g. plastic generated, cell debris, extracellular viruses
  • Built-in scalability (4 – 6 fold) for development and manufacturing using the same system
  • Automated with option to run in complete manual mode
  • No hardware change for different applications
  • Handles low to high cell density cultures (>150 million cells/mL) equally well

Advanced Cell Handling

  • Imparts low shear on cells and keeps the cells intact
  • Maintains a healthy environment to sustain cell viability
  • Complete supernatant product recovery from slurry without dilution
  • Reduces intracellular protein contamination for harvest applications by keeping the cells intact

Ensures cGMP Manufacturing

  • Closed system with single-use class VI product contact surfaces
  • Simple, robust, and scalable
  • One software for all systems
  • Clog-free and continuous operation


  • Harvest | Clarification
  • Cell Therapy
  • Vaccine Manufacturing
  • Blood Processing


kSep® Systems
en 491.8 kB