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PPA HyperCel - Mixed-mode Chromatography Resin

PPA HyperCel is a mixed-mode resin with an aromatic ligand exhibiting stronger hydrophobicity and providing a different selectivity in protein purification.

 

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Products (9)

PPA HyperCel, PRC Column 5 x 50, 1 mL Mixed-Mode Chromatography Resin
Item no.
PRC05X050PPAHCEL
Resin Format
Pre-packed column
Pack Volume
1 mL
PPA HyperCel - 10 L Mixed-Mode Chromatography Resin
Item no.
20260-052
Resin Format
Bulk resin
Pack Volume
10 L
PPA HyperCel - 25 mL Mixed-Mode Chromatography Resin
Item no.
20260-025
Resin Format
Bulk resin
Pack Volume
25 mL
PPA HyperCel - 5 L Mixed-Mode Chromatography Resin
Item no.
20260-045
Resin Format
Bulk resin
Pack Volume
5 L
PPA HyperCel - 100 mL Mixed-Mode Chromatography Resin
Item no.
20260-030
Resin Format
Bulk resin
Pack Volume
100 mL
PPA HyperCel, PRC Column 8 x 100, 5 mL Mixed-Mode Chromatography Resin
Item no.
PRC08X100PPAHCEL
Resin Format
Pre-packed column
Pack Volume
5 mL
PPA HyperCel - 1 L Mixed-Mode Chromatography Resin
Item no.
20260-040
Resin Format
Bulk resin
Pack Volume
1 L
PPA HyperCel, RoboColumn 200 µL, Mixed-Mode Chromatography Resin
Item no.
SR2PPA
Resin Format
Pre-packed column
Pack Volume
200 µL
PPA HyperCel, RoboColumn 600 µL, Mixed-Mode Chromatography Resin
Item no.
SR6PPA
Resin Format
Pre-packed column
Pack Volume
600 µL

PPA HyperCel resin is an industry-scalable chromatography resin designed for protein capture and impurity removal in a biopharmaceutical environment. Operating on a “mixed-mode” mechanism, with a phenlypropylamine ligand, its behavior is based on a combination of electrostatic and hydrophobic interactions of the proteins with the ligands. PPA HyperCel resin provides unique selectivities, different from those given by ion exchange or conventional HIC (hydrophobic interaction chromatography).

Features and Benefits

- High mechanical and chemical stability
- Suitable for large-scale chromatography in a biopharmaceutical environment
- Cross-linked cellulose base matrix


Applications

- Protein purification at low ionic strength by direct hydrophobic capture
- Separation of challenging mixtures, e.g. protein isoforms or proteins with very close pIs
- Orthogonal separation mechanism to ion exchange or HIC

Datasheet

HEA and PPA HyperCel Resins Mixed-mode Chromatography for Protein Separation
en 825.8 kB