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HEA HyperCel

HEA HyperCel is a mixed-mode resin with a less hydrophobic hexylamine ligand allowing protein binding at a moderate salt concentration under neutral pH.

   

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Products (9)

HEA HyperCel - 1 L
HEA HyperCel - 1 L
Item no.: 20250-041
Resin Format
Bulk resin
Pack Volume
1 L
HEA HyperCel - 5 L
HEA HyperCel - 5 L
Item no.: 20250-042
Resin Format
Bulk resin
Pack Volume
5 L
PRC Column 5x50 HEA HyperCel
PRC Column 5x50 HEA HyperCel
Item no.: PRC05X050HEAHCEL
Resin Format
Pre-packed column
Pack Volume
1 mL
HEA HyperCel - 10 L
HEA HyperCel - 10 L
Item no.: 20250-056
Resin Format
Bulk resin
Pack Volume
10 L
PRC Column 8x100 HEA HyperCel
PRC Column 8x100 HEA HyperCel
Item no.: PRC08X100HEAHCEL
Resin Format
Pre-packed column
Pack Volume
5 mL
HEA HyperCel - 25 mL
HEA HyperCel - 25 mL
Item no.: 20250-026
Resin Format
Bulk resin
Pack Volume
25 mL
HEA HyperCel - 100 mL
HEA HyperCel - 100 mL
Item no.: 20250-033
Resin Format
Bulk resin
Pack Volume
100 mL
RoboColumn HEA HyperCel 600 µL
Resin Format
Pre-packed column
Pack Volume
600 µL
RoboColumn HEA HyperCel 200 µL
Resin Format
Pre-packed column
Pack Volume
200 µL
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HEA HyperCel resin is an industry-scalable chromatography resin designed for protein capture and impurity removal in a biopharmaceutical environment. Operating on a “mixed-mode” mechanism, with a hexylamine ligand, its behavior is based on a combination of electrostatic and hydrophobic interactions of the proteins with the ligands. HEA HyperCel resin provides unique selectivities, different from those given by ion exchange or conventional HIC (hydrophobic interaction chromatography).

Features and Benefits

- High mechanical and chemical stability
- Suitable for large-scale chromatography in a biopharmaceutical environment
- Cross-linked cellulose base matrix


Applications

- Protein purification at low ionic strength by direct hydrophobic capture
- Separation of challenging mixtures, e.g. protein isoforms or proteins with very close pIs
- Orthogonal separation mechanism to ion exchange or HIC

Datasheet

HEA and PPA HyperCel Resins Mixed-mode Chromatography for Protein Separation
en 825.8 kB