Sartobind® D A4 Sheet
Sartobind IEX membranes are macroporous, cellulose-based membranes carrying IEX ligands. Binding of charged target molecules takes place at high flow rates.
Item no.: 94IEXD42-001
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Sartobind ion exchange (IEX) membranes feature binding sites that are grafted homogenously as an approximately 0.5 - 1 µm film on the inner walls of the reinforced and cross-linked cellulose network. Diffusion time in adsorbers is negligible because of the large pores and immediate binding of the target substance to the ligands. There is no pore diffusion as given in conventional beads but film diffusion on any point of the microporous membrane structure. At convective flow conditions the movement of the molecules of the mobile phase is directed by pump pressure only. That is why membrane adsorbers feature extremely short cycle times and exceptionally high flow rate and throughput..
- High flow rate
- Simple handling
Reference ProteinBovine serum albumin
Dimensions21 cm × 29.7 cm
Membrane Area624 cm²
Membrane Thickness275 µm
Materials of Construction
Membrane MaterialStabilised reinforced cellulose
Thermal Stabilityautoclavable at 121°C
Chemical CompatibilityStable in common chromatography buffers, unstable to peroxide and other oxidizing or reactive reagents
Ligand Density4 – 6 µeq/cm²
Pore Size3 - 5 µm
Typical Dynamic Binding Capacity 10% per mL29 mg/mL, 0.8 mg/cm²
Membrane TypeWeak anion exchanger
What you receive
- 1 manual
- 1 sheet
Flow Rate> 80 mL/cm² × min at 1 bar (14.5 psi)
pH StabilitypH 2 – 14 (short term), pH 4 – 13 (long term)
This polycarbonate filter holder has been designed for the use of 25 mm filters for the filtration of aqueous solutions.